Genomics has transformed the biological sciences. From epidemiology and medicine to evolution and forensics, the ability to determine an organism's complete genetic makeup has changed the way science is done and the questions that can be asked of it. Its most celebrated achievement was the Human Genome Project, a technologically challenging endeavor that took thousands of scientists around the world thirteen years and over three billion U.S. dollars to complete.
In this Very Short Introduction John Archibald explores the science of genomics and its rapidly expanding toolbox. Sequencing a human genome now takes only a few days and costs as little as $1,000. The genomes of simple bacteria and viruses can be sequenced in a matter of hours on a device that fits in the palm of your hand. The resulting sequences can be used to better understand our biology in health and disease and to "personalize" medicine. Archibald shows how the field of genomics is on the cusp of another quantum leap; the implications for science and society are profound.
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John Archibald is a Distinguished University Research Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Nova Scotia, Canada, and a Senior Fellow of the Canadian Institute for Advanced Research, Program in Integrated Microbial Biodiversity. He is currently an Associated Editor for Genome Biology & Evolution, and an Editorial Board member of several journals.
Sean Runnette, an Earphones Award–winning narrator, has also directed and produced more than two hundred audiobooks, including several Audie Award winners. He is a member of the American Repertory Theater company and has toured the United States and internationally with ART and Mabou Mines. His television and film appearances include Two If by Sea, Cop Land, Sex and the City, Law & Order, the award-winning film Easter, and numerous commercials.